Developmental Localization of Nephrin in Zebrafish and Medaka Pronephric Glomerulus
نویسندگان
چکیده
منابع مشابه
A Comparative Analysis of Glomerulus Development in the Pronephros of Medaka and Zebrafish
The glomerulus of the vertebrate kidney links the vasculature to the excretory system and produces the primary urine. It is a component of every single nephron in the complex mammalian metanephros and also in the primitive pronephros of fish and amphibian larvae. This systematic work highlights the benefits of using teleost models to understand the pronephric glomerulus development. The morphol...
متن کاملGenetic defects of pronephric cilia in zebrafish
Cilia play key roles in many aspects of embryogenesis and adult physiology in vertebrates. Past genetic screens in zebrafish identified numerous defects of ciliogenesis, including several mutations in the components of the intraflagellar transport machinery. In contrast to previous studies, here we describe a collection of mutants that affect subpopulations of cilia. Mutant embryos are characte...
متن کاملPodocalyxin regulates pronephric glomerular development in zebrafish
Vertebrate glomerular podocytes possess a highly sialylated transmembrane glycoprotein, Podocalyxin. In mammals, the sialic acid of Podocalyxin plays a crucial role in the formation of the characteristic podocyte architecture required for glomerular filtration. We examined the function of Podocalyxin in the developing zebrafish pronephros by disrupting the expression of podocalyxin through the ...
متن کاملZebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry.
Comparison between related species is a successful approach to uncover conserved and divergent principles of development. Here, we studied the pattern of epithalamic asymmetry in zebrafish (Danio rerio) and medaka (Oryzias latipes), two related teleost species with 115-200 Myr of independent evolution. We found that these species share a strikingly conserved overall pattern of asymmetry in the ...
متن کامل11-P010 Zebrafish and medaka: Model organisms for a comparative developmental approach of brain asymmetry
Despite recent progress in understanding of how left–right (L– R) asymmetry is generated during vertebrate development, many important questions still unanswered. One such question concerns the mechanism by which the signal responsible for the generation of L–R asymmetry is transferred from the node to the lateral plate. This signal, whose identity remains unknown, is generated in the node, and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2013
ISSN: 0022-1554,1551-5044
DOI: 10.1369/0022155413477115